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San Diego ( SAN dee-AY-goh, Spanish: [san ˈdjeɣo]) is a city in the U.S. state of California located alongside the Pacific Ocean in Southern California. With a population of over 1.3 million residents, the city is the eighth-most populous in the United States and the second-most populous in California after Los Angeles. The city is located immediately adjacent to the Mexico–United States border and is the seat of San Diego County, which has a population of nearly 3.3 million people as of 2021. San Diego is known for its mild year-round Mediterranean climate, extensive beaches and parks, its long association with the United States Navy, and its recent emergence as a healthcare and biotechnology development center. Historically home to the Kumeyaay Native Americans, San Diego has been referred to as the Birthplace of California, since it was the first site visited and settled by Europeans on what is now the West Coast of the United States. Upon landing in San Diego Bay in 1542, Juan Rodríguez Cabrillo claimed the area for Spain, forming the basis for the settlement of Alta California 200 years later.
